Ultrasonic lab Homogenizer Sonicator Cell Disruptor Price Probe Ultrasound Homogenizer

Ultrasonic lab Homogenizer Sonicator Cell Disruptor Price Probe Ultrasound Homogenizer

The effects of ultrasound on cells mainly include thermal effects, cavitation effects, and mechanical effects. The thermal effect is that when ultrasound propagates in the medium, friction hinders the molecular vibrations caused by ultrasound, causing some energy to be converted into local high heat (42-43 ℃). This is because the critical lethal temperature of normal tissue is 45.7 ℃, and tumor tissue is more sensitive than normal tissue. Therefore, at this temperature, the metabolism of tumor cells is disrupted, and DNA, RNA, and protein synthesis are affected, thereby killing cancer cells without affecting normal tissue. The cavitation effect is the formation of vacuoles in organisms under ultrasound irradiation, which generate mechanical shear pressure and turbulence with the vibration and violent explosion of the vacuoles, causing tumor bleeding, tissue disintegration, and necrosis. In addition, when the cavitation bubble ruptures, it generates instantaneous high temperatures (about 5000 ℃) and high pressures (up to 500 × 104Pa) can cause the thermal dissociation of water vapor to produce. OH radicals and. H atoms. The redox reaction caused by. OH radicals and. H atoms can lead to polymer degradation, enzyme inactivation, lipid peroxidation, and cell killing. The mechanical effect is the primary effect of ultrasound. During the propagation process of ultrasound, the alternating compression and extension of the medium particles constitute a pressure change, causing damage to the cell structure. The strength of the killing effect is closely related to the frequency and intensity of ultrasound.

Ultrasonic lab Homogenizer Sonicator Cell Disruptor Price Probe Ultrasound Homogenizer

标签：Probe Ultrasound Homogenizer, Ultrasonic lab Homogenizer Sonicator Cell Disruptor